Cell Culture

Get more control over demanding cell culture and passaging schedules – CellPort automates workflows & assays to achieve more reliable and reproducible outcomes.

How CellPort Improves Cell Culture Outcomes

Whether you’re producing monoclonal antibodies, vaccines, or other therapeutic proteins, CellPort helps streamline and automate cell culture processes, such as:

Choosing Cells for Application
Cell Passaging
Contamination Monitoring
Cryopreservation and Reconstitution
Cell Subculturing
Adherent vs. Suspension Cell Culture
Media Preparation
Weaning Cell Cultures
Counting Cells
Yield and Viability Optimization
Biopharmaceutical
From generic drug development to in vitro efficacy testing, cells aid in the end-to-end production of modern medicines. How biopharma R&D and manufacturing labs manage cells makes all the difference between getting FDA approval for commercial products, or not. CellPort helps your lab achieve more reproducible, ready-to-scale results. 
Biotechnology
Built to optimize all upstream and downstream bioprocessing operations, CellPort helps biotech companies to experiment, develop, and manufacture – CellPort makes it easy to manage your end-to-end operations, from cell lineage tracing to product packaging and beyond. CellPort helps your lab scale commercial products that adhere to GLP and GMP standards.
CRO & CDMO
For contract research and development labs to operate more efficiently, CellPort supports adherence to SOPs through automated time & scheduling, centralized communications, customized reporting, and a library of configurable protocols and assays.
Cellular Agriculture
Harvest a more plentiful cell culture – CellPort helps ensure a reliable and consistent supply of cells, with complete tracking and oversight into the scaffolds, serums, and cell culture environments. From R&D to GMP, CellPort delivers the tools you need to develop safer, purer cellular or acellular products.
Cellular Agriculture
Harvest a more plentiful cell culture – CellPort helps ensure a reliable and consistent supply of cells, with complete tracking and oversight into the scaffolds, serums, and cell culture environments. From R&D to GMP, CellPort delivers the tools you need to develop safer, purer cellular or acellular products.

Cell Lineage & Passaging

Cell lineage forms an understanding of how cells relate to one another as they proliferate and differentiate – like mapping a family tree, but for cells – and helps scientists monitor the health, quality, and integrity of cell cultures over time.

Centralized monitoring platforms like CellPort make it easy to develop traceable and reproducible cell cultures customized to your desired assay endpoint, while closely monitoring
high-passage cells that carry a higher risk of deviation.

For high-passage cells, any deviations from the expected cell behavior should be flagged early to prevent downstream implications and minimize the risk of contamination. Data analysis systems can be used along with automated monitoring systems to detect any early signs of contamination before they cause massive drains on financial resources and time.

Cell Counting

Cell counting is a fundamental process in many biological experiments – Scientists assessing drug compound toxicity, cytotoxicity, cell proliferation, cell confluence, or inhibition of cell division must measure the quantity, or density, of cells in a certain well.

This is often performed via cell imaging – typically accomplished using brightfield or fluorescent markers along with an automated imaging system and analysis software. Automated data collection and scheduled workflows surrounding cell imaging can greatly expedite the cell counting process while reducing the risk of human error.

Media Preparation

Culture media serve as an energy source for cell growth during the cell culture process. When working with unicellular and multicellular organisms (i.e., prokaryotic and eukaryotic, respectively), how the media is selected and prepared is highly dependent on the culture type, purpose of cultivation, and cell density requirements.

For example, broth cultures use dehydrated media that must be dissolved in distilled water, adjusted to the final pH, and sterilized. For agar cultures, powdered media is dissolved and stirred in distilled water, then boiled or autoclaved, and finally poured into sterile Petri dishes using aseptic techniques. Each type of culture requires specific media selection and preparation techniques, and due to the sensitive nature of cells, the slightest change will result in varying outcomes.

With step-by-step instructions (i.e., recipes) including past notes and observations, CellPort’s digital protocols ensure the right steps are taken at the right time. When variations occur, CellPort’s media tracking allows labs to pinpoint possible causes and correct course where necessary.
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Built by our scientists, for your scientists – Here’s how CellPort helps optimize cell culture and passaging.

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Navigating the Regulatory Landscape in Cell-Based Operations

In the intricate world of cell-based R&D, Good Laboratory Practices (GLP), and Good Manufacturing Practices (GMP) laboratories, the stakes couldn't be higher—pioneering research and life-saving therapeutics stand as the pillar of achievements. Yet, the stakes are equally high in the realm of regulatory compliance. Stringent standards such as 21 CFR Part 11, Annex 11, ISO 27001, and GAMP 5, 2 ed. are not just demanding; they're the prerequisites for scientific veracity and patient safety.

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Transforming Stem Cell Operations with Advanced Scheduling and Recording Systems

The challenges facing cell-based laboratories are daunting, but the solutions are within reach. By harnessing the power of SaaS platforms designed with high-stakes cell cultures in mind, labs can not only mitigate these challenges but transform them into opportunities for enhanced efficiency and progress.

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Empowering Cell-Based Operations with SaaS: A Digital Safety Net

The deployment of SaaS solutions within cell-based laboratories represents a paradigm shift in operational management. By addressing the unique challenges faced by these institutions through digital transformation, SaaS equips them with the tools and framework they need to not only survive but to innovate and lead in the forefront of cellular research. Its ability to streamline knowledge management, upskill employees, optimize operations, manage turnover, and enhance collaboration marks a pivot toward a future where efficiency and efficacy go hand in hand.

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Research
9/20/24
The Importance of FAIR Data in Cell-Based Operations

Despite the challenges, adhering to FAIR data standards presents numerous benefits that can transform the way cell-based research is conducted and utilized.

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Discover CellPort - The World's First All-in-One Cell Management Platform
CellPort Connect - CC 109: CROs, CDMOs, and Outsourcing
CellPort Connect - CC 108: How COVID Changed the Lab
CellPort Connect - CC 107: Improving Academic Training & Research
CellPort Connect - CC 106: Building Trust with Transparency
CellPort Connect - CC 105: Why Software Needs to Scale with You
CellPort Connect - CC 104: Artificial Intelligence and Clean Data
CellPort Connect - CC 102: Standardization by Design
CellPort Connect - CC 101: We Hear You
CellPort Connect - CC 103: Upskilling the Next Generation