Cell Banking
Achieve a consistent, reproducible supply of cells that are fully characterized and fully compliant with Research, GLP, and GMP needs.
How CellPort
Improves Cell Banking
Whether you’re producing monoclonal antibodies, vaccines, or other therapeutic proteins, CellPort helps streamline and automate cell culture processes, such as:
Why Scientists Love
CellPort
Watch this guided walkthrough to see a scientist use CellPort in running a real protocol.
Cell Line Authentication
To create useful master cell banks (MCB) and working cell banks(WCB), the cell line must be identified with precision, typically completed via short tandem repeat (STR) or
whole-genome sequencing (WGS) testing to compare the DNA profiles of cell lines with a referential database. From there, to ensure the cell line remains pure and safe from contamination, labs typically conduct mycoplasma and sterility testing, along with regular viability assurance (i.e., regularly thawing a test vial for confirmation).
To prevent cross-contamination, labs should maintain separate equipment, practice strict aseptic techniques, and avoid shared workspaces or locations for each cell line. CellPort helps labs to schedule and track the completion of cell line authentication processes, and trace the lineage of cell lines over time.
Master Cell Bank Creation
Why create a master cell bank? – Master cell banks (MCB) ensure cell line integrity by preserving original cells that can be used if more cells need to be grown, or if cellular metobolics are altered due to excessive passaging or changes in media.
To create MCB, labs begin by selecting a cell of interest and expanding the cell line to an adequate scale; this is typically performed via cell culture. Once the cell density is satisfactory, the cells are cryopreserved in vials and placed in long-term storage. From there, labs characterize the cells through various means, documenting factors such as growth kinetics, morphology, and relevant genetic markers.
MCBs must be preserved under precise conditions with around-the-clock monitoring in a safe, secure location, and regularly thawed and cultured to assess viability, identity, and functionality over time – this is known as stability testing. CellPort’s automated workflows and assays help labs expedite the creation of MCBs, conduct regular testing, and ensure the ongoing safety and reliability of cell lines.
Working Cell Bank Preparation
Bank Preparation
Working cell banks (WCBs) are derived from the MCB and serve as the source of cells to be used in experimentation and production. Before usage, cells from the WCB must undergo tests to ensure that they are viable, that they accurately reflect the MCB characteristics, and that they have not been contaminated.
The use of a WCB enables consistency and reproducibility in cell lines, and this
two-tiered cell bank (MCB and WCB)
system also allows for well-characterized banks at significant cost savings. To help
get products to market faster, automated systems like CellPort streamline the WCB testing process and ensure that all steps are GMP compliant, with easy-to-use reporting tools that simplify regulatory audits.
Explore More Solutions
Cell Culture
Create and maintain optimal conditions for cell growth, health, and productivity.
Learn More
Bioprocessing
Reduce your lab-to-market time with optimized upstream & downstream processes.
Learn MoreCellPort Features
Built by our scientists, for your scientists – Here’s how Cellport helps optimize cell culture and passaging.
Master Batch Records
Streamline cell manufacturing in a safe and compliant lab environment.
Collaboration
Keep offline communication online for better transparency, traceability, and training.
Learn More
Customized Reporting
Monitor the status of your lab with real-time reporting and data analysis.
Secure Cloud
CellPort is built on the cloud platform trusted by 95%of Fortune 500 companies, designed from the ground up to keep your data safe.
CellPort Learning Hub
Browse our latest resources to learn more about how CellPort streamlines life sciences.
Products Videos
View all Videos
.webp)
.webp)
Latest Blogs
View all Blogs
The challenges facing cell-based laboratories are daunting, but the solutions are within reach. By harnessing the power of SaaS platforms designed with high-stakes cell cultures in mind, labs can not only mitigate these challenges but transform them into opportunities for enhanced efficiency and progress.
...Read more
The deployment of SaaS solutions within cell-based laboratories represents a paradigm shift in operational management. By addressing the unique challenges faced by these institutions through digital transformation, SaaS equips them with the tools and framework they need to not only survive but to innovate and lead in the forefront of cellular research. Its ability to streamline knowledge management, upskill employees, optimize operations, manage turnover, and enhance collaboration marks a pivot toward a future where efficiency and efficacy go hand in hand.
...Read more
Despite the challenges, adhering to FAIR data standards presents numerous benefits that can transform the way cell-based research is conducted and utilized.
...Read more
In the intricate world of cell-based research, documentation serves as the reliable, indisputable chronicle of a lab's endeavors. A well-documented process is akin to a map that helps researchers retrace their steps or paves the way for others to follow, ensuring the solidity of scientific breakthroughs
...Read more
White Papers
.webp)
Leadership Videos
View all Videos
