Cell Banking
Achieve a consistent, reproducible supply of cells that are fully characterized and fully compliant with Research, GLP, and GMP needs.
How CellPort
Improves Cell Banking
To optimize the isolation, characterization, freezing, and storage of cells, CellPort streamlines and automates cell banking processes, such as:
Why Scientists Love
CellPort
Watch this guided walkthrough to see a scientist use CellPort in running a real protocol.
Cell Line Authentication
To create useful master cell banks (MCB) and working cell banks (WCB), the cell line must be identified with precision, typically completed via short tandem repeat (STR) or whole-genome sequencing (WGS) testing to compare the DNA profiles of cell lines with a referential database. From there, to ensure the cell line remains pure and safe from contamination, labs typically conduct mycoplasma and sterility testing, along with regular viability assurance (i.e., regularly thawing a test vial for confirmation).
To prevent cross-contamination, labs should maintain separate equipment, practice strict aseptic techniques, and avoid shared workspaces or locations for each cell line. CellPort helps labs to schedule and track the completion of cell line authentication processes, and trace the lineage of cell lines over time.
Master Cell Bank Creation
To create MCB, labs begin by selecting a cell of interest and expanding the cell line to an adequate scale; this is typically performed via cell culture. Once the cell density is satisfactory, the cells are cryopreserved in vials and placed in long-term storage. From there, labs characterize the cells through various means, documenting factors such as growth kinetics, morphology, and relevant genetic markers.
MCBs must be preserved under precise conditions with around-the-clock monitoring in a safe, secure location, and regularly thawed and cultured to assess viability, identity, and functionality over time – this is known as stability testing. CellPort’s automated workflows and assays help labs expedite the creation of MCBs, conduct regular testing, and ensure the ongoing safety and reliability of cell lines.
Working Cell Bank Preparation
The use of a WCB enables consistency and reproducibility in cell lines, and this
two-tiered cell bank (MCB and WCB)
system also allows for well-characterized banks at significant cost savings. To help get products to market faster, automated systems like CellPort streamline the WCB testing process and ensure that all steps are GMP compliant, with easy-to-use reporting tools that simplify regulatory audits.
Explore More Solutions
Cell Culture
Create and maintain optimal conditions for cell growth, health, and productivity.
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Bioprocessing
Reduce your lab-to-market time with optimized upstream & downstream processes.
Learn MoreCellPort Features
Built by our scientists, for your scientists – Here’s how Cellport helps optimize cell culture and passaging.
Digital Protocols
Choose from a library of pre-built or custom digital workflows and assays.
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Master Batch Records
Streamline cell manufacturing in a safe and compliant lab environment.
Collaboration
Maintain communication integrity online for better transparency, traceability, and training.
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Customized Reporting
Monitor the status of your lab with real-time reporting and data analysis.
Secure Cloud
CellPort is built on the cloud platform trusted by 95%of Fortune 500 companies, designed from the ground up with data integrity in mind.
CellPort Learning Hub
Browse our latest resources to learn more about how CellPort streamlines life sciences.
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CellPort Software optimizes cell culture management, reducing errors and improving efficiency. Track media, schedule tasks, and access cell history in real-time with barcode scanning and custom reporting.
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In the intricate world of cell-based R&D, Good Laboratory Practices (GLP), and Good Manufacturing Practices (GMP) laboratories, the stakes couldn't be higher—pioneering research and life-saving therapeutics stand as the pillar of achievements. Yet, the stakes are equally high in the realm of regulatory compliance. Stringent standards such as 21 CFR Part 11, Annex 11, ISO 27001, and GAMP 5, 2 ed. are not just demanding; they're the prerequisites for scientific veracity and patient safety.
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